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vikos77/README.md

Vigneshwaran Muthuraman

LinkedIn Email

Bioinformatics Researcher | Antimicrobial Resistance | Bacterial Defence Systems

MSc Bioinformatics graduate bridging wet-lab microbiology with computational genomics. Specializing in bacterial defence system architecture and its implications for antimicrobial resistance.

Current Research Focus

Acinetobacter Defence Systems: Analyzing 500+ bacterial genomes to map defence system distribution and their correlation with antibiotic resistance genes using DefenseFinder and PADLOC pipelines.

Repositories

Comprehensive analysis of defence system architecture in Acinetobacter species

Tools: DefenseFinder, PADLOC, CRISPRCasFinder, ResFinder

Languages: R, Bash

Key Finding: Identified novel correlations between defence, anti-defence systems, mobile genetic elements and antibiotic resistance genes.

Automated workflow for bacterial defence system analysis

Features: Genome download, defence system prediction, resistance gene prediction, IME prediction, and EDA

Built with: Snakemake, Python, Bash

Status: Production-ready

3. RNA-seq-R-vs-Python

Comparative analysis of RNA-seq workflows in R and Python

Goal: Benchmark differential expression analysis between DESeq2 (R) and alternative Python implementations

Status: In development

Technical Skills

Bioinformatics: NGS analysis • Bacterial genomics • Defense system prediction • Transcriptomics

Languages: R • Python • Bash • SQL

Key Tools: DESeq2 • DefenseFinder • PADLOC • Snakemake • Galaxy

Recent Achievements

Analyzed 500+ Acinetobacter genomes for defence system patterns

Developed automated pipelines reducing analysis time by 70%

Published 3 peer-reviewed papers on antimicrobial resistance

Currently seeking opportunities in bacterial genomics, antimicrobial resistance research, and bioinformatics pipeline development.

📧 vigneshwaran0594@gmail.com

Pinned Loading

  1. Acinetobacter-defence-systems Acinetobacter-defence-systems Public

    Genomic analysis of bacterial defence systems in Acinetobacter species revealing adaptive trade-offs with antimicrobial resistance evolution

    R

  2. transcriptomics-workflows transcriptomics-workflows Public

    Python

  3. acinetobacter-defence-pipeline acinetobacter-defence-pipeline Public

    Comprehensive bioinformatics pipeline analyzing bacterial defence systems and antimicrobial resistance in Acinetobacter species

    Python 1

  4. metagenomics_wound_microbiome metagenomics_wound_microbiome Public

    Bioinformatic analysis of diabetic wound microbiome

    Python 1