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Drug response classier

R package use for classify ovarian cancer patients drug response by CA125 profile

This function classifies drug response by using CA125 history profile

Requirement

library ggplot2 library grid

Usage

Bluejay.classify(input file, Day_limit=200,CA125_limit=500,CA125_bound=35)

Arguments

  • inputfile: CA125 pd file
  • patient_name: name of the patient
  • Days_plot: days after the first CA125 test
  • Day_limit: time period, this function will classify patient base on the CA125 history of these days + 21 (3 weeks) after surgery
  • CA125_limit: CA125 upper limit when plotting
  • CA125_bound: CA125 value lower bound, we will consider this patient temporary cured if her CA125 value lower than this number
  • dfs: default 21 days (3 weeks) after surgery

Return

A drug response label: non-determined, sensitive, resistant

Install

Download zip file and use install.package function in R to install R CMD INSTALL --merge-multiarch Bluejay_*.tar.gz

Example

library(ggplot2) library(grid) library(Bluejay) Bluejay.classify('OCI 1021.pd','1021')

Pipeline bash script

R -q -e "library(Bluejay);library(ggplot2);library(grid);Bluejay.classify('OCI 1021.pd','1021')"

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