diff --git a/lib/web/cache/cache.js b/lib/web/cache/cache.js
index 70a3787a71d..d1e1e3c5dee 100644
--- a/lib/web/cache/cache.js
+++ b/lib/web/cache/cache.js
@@ -4,12 +4,12 @@ const assert = require('node:assert')
 
 const { kConstruct } = require('../../core/symbols')
 const { urlEquals, getFieldValues } = require('./util')
-const { kEnumerableProperty, isDisturbed } = require('../../core/util')
+const { kEnumerableProperty, isDisturbed, isBuffer } = require('../../core/util')
 const { webidl } = require('../webidl')
 const { cloneResponse, fromInnerResponse, getResponseState } = require('../fetch/response')
 const { Request, fromInnerRequest, getRequestState } = require('../fetch/request')
 const { fetching } = require('../fetch/index')
-const { urlIsHttpHttpsScheme, readAllBytes } = require('../fetch/util')
+const { urlIsHttpHttpsScheme, readAllBytes, readableStreamClose } = require('../fetch/util')
 const { createDeferredPromise } = require('../../util/promise')
 
 /**
@@ -793,6 +793,34 @@ class Cache {
 
     // 5.5.2
     for (const response of responses) {
+      // Fix for https://github.com/nodejs/undici/issues/4710
+      // The cached response's stream may have been cancelled by the FinalizationRegistry
+      // when a previous Response object wrapping this inner response was garbage collected.
+      // If the stream is unusable but we have the body source (which cache.put() always
+      // stores), recreate the stream from the source.
+      if (response.body != null) {
+        const { stream, source } = response.body
+        const streamUnusable = stream.locked || isDisturbed(stream)
+
+        if (streamUnusable && (typeof source === 'string' || isBuffer(source))) {
+          response.body.stream = new ReadableStream({
+            pull (controller) {
+              const buffer = typeof source === 'string'
+                ? Buffer.from(source, 'utf-8')
+                : source
+
+              if (buffer.byteLength) {
+                controller.enqueue(new Uint8Array(buffer))
+              }
+
+              queueMicrotask(() => readableStreamClose(controller))
+            },
+            start () {},
+            type: 'bytes'
+          })
+        }
+      }
+
       // 5.5.2.1
       const responseObject = fromInnerResponse(response, 'immutable')
 
diff --git a/test/cache/cache.js b/test/cache/cache.js
index 4a6b1ba960f..1a0be15cc68 100644
--- a/test/cache/cache.js
+++ b/test/cache/cache.js
@@ -3,6 +3,7 @@
 const { throws } = require('node:assert')
 const { test } = require('node:test')
 const { Cache } = require('../../lib/web/cache/cache')
+const { caches, Response } = require('../../')
 
 test('constructor', () => {
   throws(() => new Cache(null), {
@@ -10,3 +11,44 @@ test('constructor', () => {
     message: 'TypeError: Illegal constructor'
   })
 })
+
+// https://github.com/nodejs/undici/issues/4710
+test('cache.match should work after garbage collection', async (t) => {
+  const cache = await caches.open('test-gc-cache')
+
+  t.after(async () => {
+    await caches.delete('test-gc-cache')
+  })
+
+  const url = 'https://example.com/test-gc'
+  const testData = { answer: 42 }
+
+  await cache.put(url, Response.json(testData))
+
+  // Call match multiple times with GC pressure between calls
+  // The bug manifests when the temporary Response object from fromInnerResponse()
+  // is garbage collected, which triggers the FinalizationRegistry to cancel
+  // the cached stream.
+  for (let i = 0; i < 20; i++) {
+    // Create significant memory pressure to trigger GC
+    // eslint-disable-next-line no-unused-vars
+    const garbage = Array.from({ length: 30000 }, () => ({ value: Math.random() }))
+
+    // Force GC if available (run with --expose-gc)
+    if (global.gc) {
+      global.gc()
+    }
+
+    // Delay to allow FinalizationRegistry callbacks to run
+    // The bug requires time for the GC to collect the temporary Response
+    // and for the finalization callback to cancel the stream
+    await new Promise((resolve) => setTimeout(resolve, 10))
+
+    // This should not throw "Body has already been consumed"
+    const match = await cache.match(url)
+    t.assert.ok(match, `Iteration ${i}: match should return a response`)
+
+    const result = await match.json()
+    t.assert.deepStrictEqual(result, testData, `Iteration ${i}: response body should match`)
+  }
+})