diff --git a/awscli/examples/medical-imaging/create-datastore.rst b/awscli/examples/medical-imaging/create-datastore.rst
index ca8d1e86cad3..267ea053b41a 100644
--- a/awscli/examples/medical-imaging/create-datastore.rst
+++ b/awscli/examples/medical-imaging/create-datastore.rst
@@ -1,6 +1,7 @@
 **To create a data store**
 
-The following ``create-datastore`` code example creates a data store with the name ``my-datastore``. When you create a datastore without specifying a ``--lossless-storage-format``, AWS HealthImaging defaults to HTJ2K (High Throughput JPEG 2000). ::
+The following ``create-datastore`` code example creates a data store with the name ``my-datastore``.
+When you create a datastore without specifying a ``--lossless-storage-format``, AWS HealthImaging defaults to HTJ2K (High Throughput JPEG 2000). ::
 
     aws medical-imaging create-datastore \
         --datastore-name "my-datastore"
@@ -12,4 +13,20 @@ Output::
         "datastoreStatus": "CREATING"
     }
 
+**To create a data store with JPEG 2000 Lossless storage format**
+
+A data store configured with JPEG 2000 Lossless storage format will transcode and persist lossless image frames in JPEG 2000 format. Image frames can then be retrieved in 
+JPEG 2000 Lossless without transcoding. The following ``create-datastore`` code example creates a data store configured for JPEG 2000 Lossless storage format with the name ``my-datastore``. ::
+
+    aws medical-imaging create-datastore \
+        --datastore-name "my-datastore" \
+        --lossless-storage-format JPEG_2000_LOSSLESS
+
+Output::
+
+    {
+        "datastoreId": "12345678901234567890123456789012",
+        "datastoreStatus": "CREATING"
+    }
+
 For more information, see `Creating a data store <https://docs.aws.amazon.com/healthimaging/latest/devguide/create-data-store.html>`__ in the *AWS HealthImaging Developer Guide*.