differential analysis output

[sdjebali]

Dear developers,

Thanks for this nice suite of tools and all the documentation you made, it is very useful !

I just have a question about the main output file of the differential analysis using atac-seq data (and following the dendritic cell tutorial).

We obtained a file like this one:

Motif Num Protection_Score_CT_actives Protection_Score_PS_actives TC_CT_actives TC_PS_actives TF_Activity Z_score P_values
MA1537.1.NR2F1(var.2) 2033 0.8899058 0.9053513 2.661423 2.6663997 0.02042222023010254 0.24598721257592038 0.805692131310318
MA0866.1.SOX21 1372 0.32497075 0.31596145 2.0268073 2.0208952 -0.014921367168426514 -0.34702087093619943 0.7285756392089715
...

that has one TF on each row and the pvalue of the differential footprinting in the last column.

We have two main questions about it:

• does it contain a log fold change per TF and othewise can it be computed from the table or from the table and another output file ?
• what does the Z-score represent for each TF ?

Thanks and sorry if it is obvious.

Best,