diff --git a/Detectors/ITSMFT/ITS/tracking/GPU/cuda/TrackerTraitsGPU.cxx b/Detectors/ITSMFT/ITS/tracking/GPU/cuda/TrackerTraitsGPU.cxx
index a8061e872c029..82eb48a8a7663 100644
--- a/Detectors/ITSMFT/ITS/tracking/GPU/cuda/TrackerTraitsGPU.cxx
+++ b/Detectors/ITSMFT/ITS/tracking/GPU/cuda/TrackerTraitsGPU.cxx
@@ -80,8 +80,8 @@ void TrackerTraitsGPU<nLayers>::computeLayerTracklets(const int iteration, int i
                                        mTimeFrameGPU->getPositionResolutions(),
                                        this->mTrkParams[iteration].LayerRadii,
                                        mTimeFrameGPU->getMSangles(),
-                                       conf.nBlocks,
-                                       conf.nThreads,
+                                       conf.nBlocksLayerTracklets[iteration],
+                                       conf.nThreadsLayerTracklets[iteration],
                                        mTimeFrameGPU->getStreams());
   mTimeFrameGPU->createTrackletsBuffers();
   computeTrackletsInROFsHandler<nLayers>(mTimeFrameGPU->getDeviceIndexTableUtils(),
@@ -113,8 +113,8 @@ void TrackerTraitsGPU<nLayers>::computeLayerTracklets(const int iteration, int i
                                          mTimeFrameGPU->getPositionResolutions(),
                                          this->mTrkParams[iteration].LayerRadii,
                                          mTimeFrameGPU->getMSangles(),
-                                         conf.nBlocks,
-                                         conf.nThreads,
+                                         conf.nBlocksLayerTracklets[iteration],
+                                         conf.nThreadsLayerTracklets[iteration],
                                          mTimeFrameGPU->getStreams());
 }
 
@@ -144,8 +144,8 @@ void TrackerTraitsGPU<nLayers>::computeLayerCells(const int iteration)
                       this->mTrkParams[iteration].MaxChi2ClusterAttachment,
                       this->mTrkParams[iteration].CellDeltaTanLambdaSigma,
                       this->mTrkParams[iteration].NSigmaCut,
-                      conf.nBlocks,
-                      conf.nThreads);
+                      conf.nBlocksLayerCells[iteration],
+                      conf.nThreadsLayerCells[iteration]);
     mTimeFrameGPU->createCellsBuffers(iLayer);
     computeCellsHandler(mTimeFrameGPU->getDeviceArrayClusters(),
                         mTimeFrameGPU->getDeviceArrayUnsortedClusters(),
@@ -161,8 +161,8 @@ void TrackerTraitsGPU<nLayers>::computeLayerCells(const int iteration)
                         this->mTrkParams[iteration].MaxChi2ClusterAttachment,
                         this->mTrkParams[iteration].CellDeltaTanLambdaSigma,
                         this->mTrkParams[iteration].NSigmaCut,
-                        conf.nBlocks,
-                        conf.nThreads);
+                        conf.nBlocksLayerCells[iteration],
+                        conf.nThreadsLayerCells[iteration]);
   }
 }
 
@@ -191,8 +191,8 @@ void TrackerTraitsGPU<nLayers>::findCellsNeighbours(const int iteration)
                                                      currentLayerCellsNum,
                                                      nextLayerCellsNum,
                                                      1e2,
-                                                     conf.nBlocks,
-                                                     conf.nThreads);
+                                                     conf.nBlocksFindNeighbours[iteration],
+                                                     conf.nThreadsFindNeighbours[iteration]);
 
     mTimeFrameGPU->createNeighboursDevice(iLayer, nNeigh);
 
@@ -207,8 +207,8 @@ void TrackerTraitsGPU<nLayers>::findCellsNeighbours(const int iteration)
                                  currentLayerCellsNum,
                                  nextLayerCellsNum,
                                  1e2,
-                                 conf.nBlocks,
-                                 conf.nThreads);
+                                 conf.nBlocksFindNeighbours[iteration],
+                                 conf.nThreadsFindNeighbours[iteration]);
 
     nNeigh = filterCellNeighboursHandler(mTimeFrameGPU->getDeviceNeighbourPairs(iLayer),
                                          mTimeFrameGPU->getDeviceNeighbours(iLayer),
@@ -247,8 +247,8 @@ void TrackerTraitsGPU<nLayers>::findRoads(const int iteration)
                                         this->mTrkParams[0].MaxChi2NDF,
                                         mTimeFrameGPU->getDevicePropagator(),
                                         this->mTrkParams[0].CorrType,
-                                        conf.nBlocks,
-                                        conf.nThreads);
+                                        conf.nBlocksProcessNeighbours[iteration],
+                                        conf.nThreadsProcessNeighbours[iteration]);
     }
     // fixme: I don't want to move tracks back and forth, but I need a way to use a thrust::allocator that is aware of our managed memory.
     if (trackSeeds.empty()) {
@@ -269,8 +269,8 @@ void TrackerTraitsGPU<nLayers>::findRoads(const int iteration)
                      this->mTrkParams[0].MaxChi2NDF,                   // float maxChi2NDF
                      mTimeFrameGPU->getDevicePropagator(),             // const o2::base::Propagator* propagator
                      this->mTrkParams[0].CorrType,                     // o2::base::PropagatorImpl<float>::MatCorrType
-                     conf.nBlocks,
-                     conf.nThreads);
+                     conf.nBlocksTracksSeeds[iteration],
+                     conf.nThreadsTracksSeeds[iteration]);
 
     mTimeFrameGPU->downloadTrackITSExtDevice(trackSeeds);
 
diff --git a/Detectors/ITSMFT/ITS/tracking/include/ITStracking/TrackingConfigParam.h b/Detectors/ITSMFT/ITS/tracking/include/ITStracking/TrackingConfigParam.h
index ef6f925f1c29f..5b4b1aca1dfb8 100644
--- a/Detectors/ITSMFT/ITS/tracking/include/ITStracking/TrackingConfigParam.h
+++ b/Detectors/ITSMFT/ITS/tracking/include/ITStracking/TrackingConfigParam.h
@@ -107,9 +107,32 @@ struct TrackerParamConfig : public o2::conf::ConfigurableParamHelper<TrackerPara
 };
 
 struct ITSGpuTrackingParamConfig : public o2::conf::ConfigurableParamHelper<ITSGpuTrackingParamConfig> {
-  // GPU-specific parameters
-  int nBlocks = 20;
-  int nThreads = 256;
+  static constexpr int MaxIter = TrackerParamConfig::MaxIter;
+
+  /// Set nBlocks/nThreads to summarily override all kernel launch parameters in each iteration.
+  /// Parameters must start with nBlocks/nThreads.
+  static constexpr int OverrideValue{-1};
+  static constexpr char const* BlocksName = "nBlocks";
+  static constexpr char const* ThreadsName = "nThreads";
+  int nBlocks = OverrideValue;
+  int nThreads = OverrideValue;
+  void maybeOverride() const;
+
+  /// Individual kernel launch parameter for each iteration
+  int nBlocksLayerTracklets[MaxIter] = {30, 30, 30, 30};
+  int nThreadsLayerTracklets[MaxIter] = {256, 256, 256, 256};
+
+  int nBlocksLayerCells[MaxIter] = {30, 30, 30, 30};
+  int nThreadsLayerCells[MaxIter] = {256, 256, 256, 256};
+
+  int nBlocksFindNeighbours[MaxIter] = {30, 30, 30, 30};
+  int nThreadsFindNeighbours[MaxIter] = {256, 256, 256, 256};
+
+  int nBlocksProcessNeighbours[MaxIter] = {30, 30, 30, 30};
+  int nThreadsProcessNeighbours[MaxIter] = {256, 256, 256, 256};
+
+  int nBlocksTracksSeeds[MaxIter] = {30, 30, 30, 30};
+  int nThreadsTracksSeeds[MaxIter] = {256, 256, 256, 256};
 
   O2ParamDef(ITSGpuTrackingParamConfig, "ITSGpuTrackingParam");
 };
diff --git a/Detectors/ITSMFT/ITS/tracking/src/Tracker.cxx b/Detectors/ITSMFT/ITS/tracking/src/Tracker.cxx
index b0add9881d01b..c8bf39142e019 100644
--- a/Detectors/ITSMFT/ITS/tracking/src/Tracker.cxx
+++ b/Detectors/ITSMFT/ITS/tracking/src/Tracker.cxx
@@ -39,6 +39,7 @@ Tracker::Tracker(TrackerTraits7* traits) : mTraits(traits)
   /// Initialise standard configuration with 1 iteration
   mTrkParams.resize(1);
   if (traits->isGPU()) {
+    ITSGpuTrackingParamConfig::Instance().maybeOverride();
     ITSGpuTrackingParamConfig::Instance().printKeyValues(true, true);
   }
 }
diff --git a/Detectors/ITSMFT/ITS/tracking/src/TrackingConfigParam.cxx b/Detectors/ITSMFT/ITS/tracking/src/TrackingConfigParam.cxx
index b5fbedcc89339..3101c34d4ab8f 100644
--- a/Detectors/ITSMFT/ITS/tracking/src/TrackingConfigParam.cxx
+++ b/Detectors/ITSMFT/ITS/tracking/src/TrackingConfigParam.cxx
@@ -9,8 +9,36 @@
 // granted to it by virtue of its status as an Intergovernmental Organization
 // or submit itself to any jurisdiction.
 
+#include <boost/property_tree/ptree.hpp>
+
+#include "Framework/Logger.h"
 #include "ITStracking/TrackingConfigParam.h"
 
 O2ParamImpl(o2::its::VertexerParamConfig);
 O2ParamImpl(o2::its::TrackerParamConfig);
 O2ParamImpl(o2::its::ITSGpuTrackingParamConfig);
+
+namespace o2::its
+{
+
+void ITSGpuTrackingParamConfig::maybeOverride() const
+{
+  if (nBlocks == OverrideValue && nThreads == OverrideValue) {
+    return;
+  }
+  const auto name = getName();
+  auto members = getDataMembers();
+  for (auto member : *members) {
+    if (!member.name.ends_with(BlocksName) && !member.name.ends_with(ThreadsName)) {
+      if (nBlocks != OverrideValue && member.name.starts_with(BlocksName) && (member.value != nBlocks)) {
+        o2::conf::ConfigurableParam::setValue<int>(name, member.name, nBlocks);
+      }
+      if (nThreads != OverrideValue && member.name.starts_with(ThreadsName) && (member.value != nThreads)) {
+        o2::conf::ConfigurableParam::setValue<int>(name, member.name, nThreads);
+      }
+    }
+  }
+  LOGP(info, "Overwriting gpu threading parameters");
+} // namespace o2::its
+
+} // namespace o2::its