diff --git a/prodtests/full-system-test/dpl-workflow.sh b/prodtests/full-system-test/dpl-workflow.sh
index b51594115154c..b683fd88d12bc 100755
--- a/prodtests/full-system-test/dpl-workflow.sh
+++ b/prodtests/full-system-test/dpl-workflow.sh
@@ -269,6 +269,7 @@ if [[ $GPUTYPE == "HIP" ]]; then
     TIMESLICEOFFSET=$(($GPU_FIRST_ID + ($NUMAGPUIDS != 0 ? ($NGPUS * $NUMAID) : 0)))
     GPU_CONFIG+=" --environment \"ROCR_VISIBLE_DEVICES={timeslice${TIMESLICEOFFSET}}\""
   fi
+  [[ $EPNSYNCMODE == 1 || ! -z ${OPTIMIZED_PARALLEL_ASYNC:-} ]] && [[ ${EPN_NODE_MI100:-} == "1" ]] && [[ ${DISABLE_MI100_SERIALIZATION:-0} != 1 ]] && GPU_CONFIG_KEY+="GPU_proc.serializeGPU=3;"
   #export HSA_TOOLS_LIB=/opt/rocm/lib/librocm-debug-agent.so.2
 else
   GPU_CONFIG_KEY+="GPU_proc.deviceNum=-2;"